Liver Function

If your liver is not functioning well, you will not notice this for a long time. Symptoms and complaints that may indicate an abnormality in the liver often resemble everyday symptoms and complaints. In many cases, liver disease only occurs after serious damage has already occurred. An abnormality is therefore often only discovered late - too late, in some cases.

Symptoms that may occur with liver disease include swelling of the liver, jaundice, and fatigue.

The liver is essential for our health and it has important functions:

  • Converting waste so that it can be excreted (removal of toxic substances from the body);
  • The metabolism and storage of fats, proteins and carbohydrates (the conversion and storage of substances containing energy);
  • The formation of bile, a liquid that allows fat-soluble substances to leave the body through the liver and allows fats and fat-soluble vitamins to be obtained from food.

To detect liver problems at an early stage, it is advisable to have your liver function checked. Liver problems increase the risk of liver disease and cardiovascular disease.

This test gives you insight into your liver function. To provide an indication of your liver function, tests assess the following markers:

  • ALT;
    • A liver enzyme that can be measured to diagnose liver disease.
  • Gamma-GT (gGT)
    • An enzyme made in the liver that helps convert certain amino acids (such as AST and ALT).
  • icon It is completely anonymous;
  • icon You can always come to us:
  • icon You do not have to go directly to a healthcare provider;
  • icon The test is as reliable as the one used in hospitals;
  • icon Our clinical chemist will assess your results and give you tailored advice;

Markers and consequences


ALT (alanine aminotransferase) is a liver enzyme that is measured to diagnose liver disease. An enzyme is a protein that converts one substance into another. This happens when alcohol or medicines are broken down, for example. ALT is mainly present in the liver, but is also found in small amounts in muscles, the kidneys and heart. When liver cells become damaged, ALT leaks from the liver into the blood. This causes an increase in the concentration of ALT in the blood. This can happen before there are any signs or symptoms that may indicate liver damage. Since ALT is primarily present in the liver, it is the most specific marker to identify possible damage to liver cells.


Gamma-GT (gGT)

Gamma-glutamyltransferase (Gamma-GT or GGT) is an enzyme made in the liver that helps convert certain amino acids (such as AST and ALT). Gamma-GT is also present in the kidneys, pancreas, spleen, heart and brain. Normally the concentration of Gamma-GT in the blood is very low, but when the liver is having to work hard, the amount can rise considerably. This happens when many substances arrive in the liver for processing in a short period of time, for example due to (extreme) use of alcohol or medicines.



The most common causes of liver disease are:

  • Alcohol use/abuse
  • Medicine use
  • Viruses, for example Hepatitis
  • Congenital defects
  • Metabolic diseases

The liver has a large reserve capacity: if one part of the liver is not working properly, another part can work harder to make up for the shortfall without too much effort. The disadvantage of this is that liver problems are often only discovered at a more advanced stage.

Liver problems can involve various diseases:

  • Liver cirrhosis (scarring of the liver)
  • A liver tumour
  • Hepatitis
  • Fatty liver

Our Liver Function test 

The Liver Function test that we offer at How Are You Diagnostics is the same laboratory test that is also performed by hospital laboratories. 

We distinguish ourselves by offering the majority of our tests via a self-test kit. This means that you can have our tests delivered to any postal address, after which you can take the sample for the chosen test yourself at any time. So you can take your sample at home, just like with a self-test/home test.

For some markers you can also buy a self-test at the drugstore or pharmacy. For these, you put a drop of blood on a special strip and the result is displayed immediately. The self-test gives you an impression of the level of the marker in the blood. 

With a self-test you have to interpret the result yourself, which is difficult if you are not qualified to do this like a clinical chemist. It is more reliable to perform the test in a laboratory with the appropriate equipment and have the result determined by a clinical chemist. 

Similar tests from your GP or hospital are often twice as expensive. You also have to make an appointment and go to the appointment to do a blood test

How does it work?

Wij hebben speciale thuis testen ontwikkeld zodat jij ze gemakkelijk thuis, op ieder gewenst moment, kunt uitvoeren. Het geeft snel zekerheid en helpt belangrijke vragen te beantwoorden.

Om de test uit te voeren maakt u gebruik van onze How Are You Diagnostics App. Deze App is te downloaden in de App Store en de Google Play Store. Hierin maakt u een persoonlijk account aan, koppelt u de test aan uw account en wordt u stap voor stap uitgelegd hoe u de test uitvoert. Verstuur de test en ontvang het resultaat in uw persoonlijke account van onze beveiligde App. Het is niet mogelijk om het testresultaat te ontvangen zonder het gebruik van de App.

Verstuur de test zo snel mogelijk na afname; dit kan gratis via een reguliere PostNL brievenbus.

De testen van How Are You Diagnostics worden geanalyseerd in ons eigen ISO 15189 en NEN 7510 gecertificeerde laboratorium en beoordeeld door onze eigen specialisten (klinisch chemicus).

Tijdens het gehele proces gaan we vertrouwelijk met uw gegevens om. Na ontvangst in het laboratorium ontvangt u binnen 5 werkdagen de resultaten in de App. U ontvangt een melding als het resultaat beschikbaar is.

Content and step-by-step plan 

Inhoud van de test:

  • informatiebrief;
  • vingerprikset (alcoholdoekje, vingerprikker, gaasje en een pleister);
  • afnamebuisje;
  • retouroplossing (RigidSafetyBag en een gefrankeerde retourenvelop).

De afname instructies zijn te vinden in de How Are You Diagnostics App.


Testen in vier stappen:

  1. Download de How Are You Diagnostics App
    Download onze App in de App Store (iOS) of Google Play Store (Android).
    Registreer een account of log in.
  2. Doe de test
    Scan de code van de buis/container of voer deze handmatig in.
    Start de afname.
  3. Verstuur de test
    Verstuur de test naar ons laboratorium.
  4. Ontvang het testresultaat
    Ontvang en bekijk het resultaat van de test in de App.